Foxl2 (forkhead box L2), one of the well-known ovarian markers, has been characterized in many clinical and basic studies to be directly associated with blepharophimosis/ptosis/epicanthus inverse syndrome (BPES)—a symptom that leads to infertility in which the patients’ ovary function is prematurely terminated [10]. Here, FOXL2 is linked to blepharophimosis, ptosis, and epicanthus inversus syndrome.