In Calu-3 cells, the relative mRNA expression upon infection with infectious SARS-CoV-2 exhibited a pronounced increase in the cases of ADGRD1/GPR133 and ADGRG7/GPR128, a small increase in the case of ADGRB3/BAI3 and a negligible change in that of ADGRV1/GPR98 mRNA levels after 24 and 48 h (Figure 2A). The gene discussed is ADGRD1; the disease is infection.