KDR and endometrium neoplasm: PA did not affect the levels of serum VEGF after 4 weeks of treatment (Supplementary Figure S2); however, the expression of Bcl-xL, VEGF-R2, phospho-42/44, and phospho-S6 in the endometrial tumors of PA-treated mice was notably decreased, while the expression of PERK was increased when compared with control mice (p = 0.015) (Figure 8G).