HNRNPA1 and malignant colon neoplasm: The HOXB-AS3 peptide can competitively bind to the arginine residue in the hnRNPA1 RGG motif and inhibit the binding of hnRNPA1 to PKM, which further down-regulates the level of PKM2 and inhibits the metabolism reprogramming process of colon cancer cells [42].