RAP1B and osteopetrosis: Moreover, label-free quantitative proteomics analysis of fluconazole-treated Dental Pulp Mesenchymal Stem/stromal cells from CA-II-deficient osteopetrosis patients has revealed potential treatment avenues for osteopetrosis by identifying differentially expressed proteins, including ATP1A2, CPOX, Ap2 alpha, RAP1B, and members of the RAB protein family [91].