SNL-induced neuropathic pain was also shown to be alleviated by the type-B monoamine oxidase (MAO-B) inhibitor, KDS2010, through competitively blocking the BDNF/trkB/NMDA-NR2B pathway [138], giving further support to the intervention of this pathway in the genesis of neuropathic pain. The gene discussed is GRIN2B; the disease is neuropathic pain.