CD4 and colitis: Additionally, the proportions of IFN-γ+CD4+ T (Th1) cells and IL-10+CD4+ T cells were increased in the CLP of DSS-induced colitis rats, while the proportions of IL-17+CD4+ T (Th17) cells and IL-4+CD4+ T (Th2) cells showed no significant difference between the two groups (Figure 2D–G).