TSAs, on the other hand, can be self-tumor antigens like epidermal growth factor receptor variant III (EGFRvIII), expressed in 25% of EGFR-expressing glioblastoma [398], or non-self viral antigens like human papillomavirus E6 and E7 proteins (HPV E6 and E7), expressed in approximately 60% of oropharyngeal cancers and almost all cervical cancers [399]. This evidence concerns the gene EGFR and neoplasm.