The molecular analysis of several of the most frequently mutated molecules in lung cancer includes V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS; 25%), anaplastic lymphoma kinase (ALK; 6%), epidermal growth factor receptor (EGFR), phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA; 3%), v-Raf murine sarcoma viral oncogene homolog B1 (BRAF; 3%), and human epidermal growth factor receptor 2 (HER2; 1%) [24]. This evidence concerns the gene PIK3CA and lung cancer.