Simultaneous treatment with CP and pharmacological inhibition of Trx also synergistically enhanced caspase 3-dependent apoptosis with some degree of lipid peroxidation-dependent ferroptosis (iron-dependent form of apoptosis linked to cytotoxic lipid peroxide accumulation) in glioblastoma cancer cells and slowed tumour growth in glioblastoma-bearing mice [145]. Here, CASP3 is linked to neoplasm.