CP and atopic eczema: In a chemically induced atopic dermatitis model in vitro and in vivo, elevated inflammation (upregulated TNFα, IL1β, and C-C motif ligand 2 (CCL2), with decreased anti-inflammatory IL10), ERS/UPR, GRP78 expression, and eventually CHOP-mediated apoptosis were observed, all of which were curtailed by CP treatment via induction of HO1 [204].