A thoughtful research was conducted by reviewing the PubMed database’s occurrences until 6th March 2024 using different combinations of keywords: “SNP”, “SNPs”, “polymorphism”, “polymorphisms”, “cancer”, “eNOS”, Endothelin-1”, “ET-1”, “Angiotensin II”, “AGT”, “ACE” and “Angiotensin Converting Enzyme”, “F2”, “Prothrombin”, “SELP”, “P-selectin”, “SELE”, “E-selectin”, “E-selectin”, “Von Willebrand factor”, “VWF”, “CD54”, “ICAM1”, “ICAM-1”, “VCAM1”, “VCAM-1” and “CD106”. Here, SELE is linked to cancer.