The study concluded that the upregulation of IL-6R, Toll-Like Receptor 4 (TLR4), Toll-Like Receptor 2 (TLR2), and IFN-γ genes can contribute to the onset of CRS in 10 patients with CRS and SARS-CoV-2 infection [121]. The gene discussed is IL6R; the disease is congenital rubella syndrome.