MITF and melanoma: Selected genes and gene sets are overexpressed in distinct areas of the image, e.g., AXL, MITF, and EZH2 in different melanoma cell-rich clusters (c2/c3, c4/c5, and c6, respectively), also upregulating the hallmark (HM) gene sets oxphos and G2/M checkpoint, respectively (Figure 5a,b; compare with Figure 3a).