In our previous report, it has been shown that MYC is overexpressed in DLBCL cell lines, including Ly1 and DHL6, and MYC suppression by JQ1 (a potent and specific BRD4 inhibitor) and 10058-F4 (a MYC-Max hetero-dimerization inhibitor) efficiently induced apoptosis in these cells, suggesting that MYC plays a critical role in survival of DLBCL cells [15]. This evidence concerns the gene BRD4 and diffuse large B-cell lymphoma.