BDNF and Alzheimer disease: Importantly, microglia produce, secrete, and recruit other secondary molecules, such as prostaglandins and growth factors like brain-derived neurotrophic factor (BDNF), and with AD, these factors are further implicated and linked to the onset and pathology of the disease, highlighting the complexity of neuroinflammation and microgliosis in the progression to a neurodegenerative state [76,77,78,79].