However, eosinophils depletion after Gal-1 binding to eosinophilic membrane glycans in sensitized mice [58] as well as IL-10 production after LPS exposure [39] would suggest a specific role for Gal-1 in the orchestration of Th2 inflammation in patients with asthma, which should be further explored in future studies. Here, LGALS1 is linked to asthma.