IL4 and gingivitis: Significantly higher levels were observed for interleukin 13 (IL-13) (p = 1.5 × 10−15 caries/gingivitis, p = 4.0 × 10−13 caries/healthy), interleukin 2-RA (IL-2-RA) (p = 3.3 × 10−6 caries/gingivitis, p = 1 × 10−4 caries/healthy), interleukin 4 (IL-4) (p = 1.5 × 10−15 caries/gingivitis, p = 4.1 × 10−13 caries/healthy), and Eotaxin/CCL11 (p = 8.1 × 10−5 caries/gingivitis, p = 4.4 × 10−4 caries/healthy) in patients with caries when compared to the other groups (healthy and gingivitis) [24].