A few of the best-characterized links to ADAR include autoimmune disorders like Aicardi-Goutières syndrome (AGS) and Bilateral Striatal Dystonia (BSD), neurological disorders like Sporadic ALS and epilepsy, and behavioral and psychiatric disorders like Major Depressive Disorder (MDD) and suicidal schizophrenia [36,37,38,39,40]⁠. This evidence concerns the gene ADAR and major depressive disorder.