THRB and breast cancer: Multivariate analyses performed by Shao et al., Ditsch et al., and Jerzak et al. demonstrated that higher THRβ1 expression (irrespective of intracellular location) is associated with significantly longer overall survival in patients diagnosed with sporadic BC with a hazard ratio of 0.55, 0.83, and 0.61, respectively [9,10,11].