Upon analyzing their DEGs, Th cells and Treg cells displayed very limited numbers of and low fold changes in upregulated genes and appeared to be immunosuppressive (Figure 6I and J): we found elevated CD52 expression levels in both Th cells and Treg cells, an immune suppressor downregulated in systemic lupus erythematosus.[24] Additionally, EMP3 was augmented in Treg cells, which was associated with immunosuppression and T‐cell exclusion in glioblastoma.[25] Furthermore, these cells showed apparent downregulation of various HSPs, including HSPA1A and HSP90AA1 (Figure 6I and J). Here, EMP3 is linked to systemic lupus erythematosus.