T lymphocytes are also critical regulators of the immune system and autoimmune diseases.[22] We subclustered T and NK cells (N = 5088) in our samples as CD4+ Th cells, CD8+ CTLs, Foxp3+ Treg cells, NK cells, and proliferating T cells (Figure 6G; Figure S8A–D, Supporting Information). This evidence concerns the gene CD4 and autoimmune disease.