The LASSO analysis identified potential prognostics factors as NIHSS, mTICI grade, CHD, diabetes, hypertension, AF, IV-tPA, age and BMI, while SVM-RFE determined gender, IV-tPA, AF, hypertension, dyslipidemia, diabetes, stroke, CHD, antithrombotic therapy, occluded site, mTICI grade, NIHSS, and Boruta established NIHSS, mTICI, CHD, AF, hypertension. The gene discussed is PLAT; the disease is stroke disorder.