MYO18B and cardiomyopathy: The pathophysiology of the cardiomyopathies is unclear, although loss-of-function mutations of myo18b in zebrafish were reported to severely impair myofibrillogenesis in fast-twitch skeletal muscle cells (Berger et al., 2017; Gurung et al., 2017), suggesting that it may be explained by impaired formation and/or maintenance of myofibrils, as speculated by Ajima et al. (2008).