Thirty‐two genes (GRAMD3, SYNGR1, CMTM7, HLA‐DMB, HLA‐DRB4, CLEC2D, CCNB1IP1, HLA‐DRA, DEFB1, ERBB2, MUC4, LOC145837, RPS24, RHOD, HBEGF, ARHGDIB, PITPNC1, PEA15, KRT16, GJB3, JUN, FHL2, CYB5R2, HLA‐B, EGR2, HERC6, DUSP5, HBA2, CHST15, NKX3‐1, LBH, TSPAN8) are common in hypopharyngeal cancer and EGFR‐mutated lung adenocarcinoma. The gene discussed is HBEGF; the disease is lung adenocarcinoma.