Thirty‐two genes (GRAMD3, SYNGR1, CMTM7, HLA‐DMB, HLA‐DRB4, CLEC2D, CCNB1IP1, HLA‐DRA, DEFB1, ERBB2, MUC4, LOC145837, RPS24, RHOD, HBEGF, ARHGDIB, PITPNC1, PEA15, KRT16, GJB3, JUN, FHL2, CYB5R2, HLA‐B, EGR2, HERC6, DUSP5, HBA2, CHST15, NKX3‐1, LBH, TSPAN8) are common in hypopharyngeal cancer and EGFR‐mutated lung adenocarcinoma. The gene discussed is HLA-B; the disease is hypopharynx cancer.