This study found that the EGFR mutation rate was 20.2% in a Chinese population with lung cancer and coexistent ILA, and the mutation frequency in patients with subpleural fibrotic ILA (3.5%) was lower than that in those with non-fibrotic ILA (38.5%), which is similar to findings in earlier studies in the Japanese population [12, 24]. Here, EGFR is linked to lung cancer.