Regarding KCNC1, a study conducted in 2016 found that 16 out of 84 clinically confirmed Progressive Myoclonic Epilepsy (PME) cases without clear genetic etiology had a monoallelic missense variant in the KCNC1 gene, c.959G > A (p.Arg320His), 13 of whom were unrelated [9]. The gene discussed is KCNC1; the disease is myoclonic epilepsy.