Conversely, in the months following acute ON, thinning of the pRNFL as well as of the macular ganglion cell inner plexiform layer (GCIPL) occurs with significantly lower pRNFL and GCIPL thickness found in MOG-ON than in both healthy controls and in MS-ON according to a recent meta-analysis [92, 93]. This evidence concerns the gene MOG and myeloid sarcoma.