It is worth mentioning that a role of TGM6 in the central nervous system, as discussed in the literature (Thomas et al. 2013), is not supported by the distribution of TGM6 mRNA in human tissues, which is limited to the skin (https://www.gtexportal.org/home/gene/TGM6), last accessed on 2024 February 9), and a hypothetical link between mutations of TGM6 and spinocerebellar ataxia (Wang et al. 2010) was refuted by a recent genetic study (Chen et al. 2020). This evidence concerns the gene TGM6 and cerebellar ataxia.