The main indicators for evaluating the degree of hepatic fibrosis include HA, LN, Collagen I, Collagen III, PCIII, PIIINP, IV-C, IL-6, and TNF-α, α-SMA, HYP, PDGF-BB, CTGF and TGF-β1. This evidence concerns the gene IL6 and Hepatic fibrosis.