Comparison of the two groups revealed a significantly higher mean age (p<0.01), CRP (p<0.05), BNP (p<0.05), CTR (p<0.01) and duration in hospitalization (p<0.001), and a significantly higher number of death within 6 months after dialysis induction (p<0.001), death during hospitalization (p<0.001), patients transferred to the hospital for inpatient dialysis (p<0.001), emergency dialysis induction using dialysis catheter (p<0.05), cardiovascular disease(p<0.005), cerebral vascular disease (p<0.05) in the frail group. Here, NPPB is linked to cardiovascular disorder.