Taking into account homeostatic disorders resulting from arterial hypertension and the key importance of CacyBP/SIP, β‐catenin and endocannabinoids in the functioning of many organs, it was decided to assess the presence and distribution of CacyBP/SIP, β‐catenin, CB1 and CB2 in the adrenal glands of hypertensive rats of various aetiology. This evidence concerns the gene CNR1 and Hypertension.