KLF4 and hepatocellular carcinoma: Taken together, we assessed our findings, a novel KLF4/Lnc18q22.2/ULBP3 axis, in HCC progression under hypoxia condition by transfecting si‐NC, si‐KLF4#1, si‐KLF4#1+ULBP3 into HCC cells and then subjected to cellular experiments upon hypoxia condition.