When inflammasomes like NLR family pyrin domain containing 3 (NLRP3) are activated, proinflammatory cytokines like interleukin-1 beta (IL-1β) and interleukin-18 (IL-18) are secreted, which can cause a persistent inflammatory state that worsens liver damage and accelerates the growth of cancer [16]. This evidence concerns the gene IL1B and cancer.