Results from the ROC curve analysis demonstrated that DCP had a specificity of 93.65% and a sensitivity of 35.44%.Our study also confirmed that AFP >400 ng/mL is consistent with the diagnosis of pathological examination in HCC (κ = 0.042, P = .013), with a specificity of approximately 100% and a sensitivity of 20.3% (Supplemental Table 2). Here, AFP is linked to hepatocellular carcinoma.