Further stratifying the PCa patients into two subgroups, namely the prognostic groups III-IV group (n=57) and Gleason score ≥ 8 group (n=31), demonstrated that in both the prognostic groups III-IV group (P=0.0434; Figure 6B) and Gleason score ≥ 8 group (P=0.0467; Figure 6C), patients with low IL-38 expression had significantly higher survival rates than those with high expression. This evidence concerns the gene IL1F10 and posterior cortical atrophy.