Regarding the HSPC clusters 2, 3, and 4, CD34+ cells from healthy adults were equally distributed to the three HSPC clusters, whereas the majority of CD34+ CB cells and only few SLE cells were present in HSPC cluster 2 compared with clusters 3 and 4, suggesting that this cluster corresponds to a primitive cell population (Figures 2A, B). The gene discussed is CD34; the disease is systemic lupus erythematosus.