High serum albumin levels reduced the risk of hypertension, using Q3 as a control, Q1 (OR, 1.30, 95% CI, 1.10–1.54), Q2 (OR, 1.08, 95% CI, 0.91–1.28), Q4 (OR, 1.03, 95% CI, 0.87–1.23) and Q5 (OR, 1.02, 95% CI, 0.86–1.21) (ptrend = 0.278) (Table 3). The gene discussed is ALB; the disease is Hypertension.