Further adjustment for smoking, alcohol consumption, diabetes, obesity, body mass index, resting heart rate, systolic and diastolic blood pressure, fasting plasma glucose, triglycerides, total cholesterol, uric acid, blood urea nitrogen, creatinine, LDL-C, HDL-C, WBC, ALT, and AST (Model 3) only slightly weakened the association but did not affect the significant association between the serum albumin high stable trajectory and the incidence of hypertension (OR, 0.70, 95% CI, 0.51–0.96) (P < 0.001). The gene discussed is GPT; the disease is hypertensive disorder.