There is a notable decrease in anti-inflammatory microorganisms, such as Faecalibacterium prausnitzii and Eubacterium rectale, in COVID-19 patients, which corresponds with elevated levels of tumor necrosis factor (TNF), interleukin-10 (IL-10), and CXCL10 [11]. The gene discussed is CXCL10; the disease is COVID-19.