Open Science Framework: Diagnostic Accuracy of 18F Prostate Specific Membrane Antigen (PSMA) PET-CT radiotracers in staging and restaging of high- risk prostate cancer patients and patients with biochemical failure: Protocol for an Overview of Reviews.https://doi.org/10.17605/OSF.IO/QMEZ524. This evidence concerns the gene FOLH1 and Familial prostate cancer.