According to transcriptome sequencing, antitumor chemokine regulatory genes (CXCR3) were upregulated, and protumor chemokine regulatory genes (CCR3, CXCL1, CXCL2, CXCL3, CXCL8, and CXCR2) were downregulated after MWA in thyroid cancer. The gene discussed is CXCR2; the disease is thyroid gland carcinoma.