According to transcriptome sequencing, antitumor chemokine regulatory genes (CXCR3) were upregulated, and protumor chemokine regulatory genes (CCR3, CXCL1, CXCL2, CXCL3, CXCL8, and CXCR2) were downregulated after MWA in thyroid cancer. The gene discussed is CXCL8; the disease is thyroid gland carcinoma.