Moreover, we further investigated the properties of CAFs for myoFib‐1 and myoFib‐2 subsets by detecting the expression of signature genes for ECM deposition and Rho signalling (Figure 3E), which are reported to play an important role in the crosstalk between CAFs, cancer cells, and tumourous physical microenvironment.29, 30, 31. Here, RHO is linked to cancer.