The six clusters were fibroblasts, marked by expression of GPX2 and PLA2G2A; tumour cells with fibrosis expressed KRT20, CLDN4, and CDH1 positively; goblet cells, identified by TFF3 and FCGBP expression; cancer‐associated fibroblasts, characterised by MYL9, TAGLN, and POSTN expression; immune cells, expressed MALAT1 and IGHG1 remarkably; and monocytes and macrophages, expressed IL1B, CCL3, and S100A9 highly (Figure 7C). Here, CLDN4 is linked to cancer.