However, different variants in the same gene can also be associated with specific phenotypes; for example, the R183Q variant in GNAQ has been associated with CM and Sturge-Weber syndrome, but not with non-involuting congenital haemangiomas (NICH) or rapid-involuting congenital haemangiomas (RICH), which are instead associated with the Q209H/L/P variants. The gene discussed is GNAQ; the disease is cutaneous mastocytosis.