Given that ICA + CUR inhibits the expression of DNMT1 in vivo, and since the ICA + CUR treatment of FMT and direct treatment with SCFAs had no significant effect on the expression of DNMT1 in vivo, the investigation would continue to determine whether ICA + CUR directly affected the expression of DNMT1 in PCa cells in vitro. This evidence concerns the gene DNMT1 and posterior cortical atrophy.