TLN1 and DNA repair disease: These genes were FANCG, UNC13B, TESK1, TLN1, and CREB3. The FANCG (Fanconi anemia complementation group G) gene, positioned between 59.75 Mb and 59.76 Mb, encodes a protein expressed in the chromosomal instability syndrome associated with various developmental abnormalities, progressive bone marrow failure, reduced fertility, retarded growth, hyperpigmentation, and a predisposition to cancer [46, 47].