Analysis of Module 6 in relation to 10 oncogenic signaling pathways (cell cycle, Hippo signaling, Myc signaling, Notch signaling, oxidative stress response/Nrf2, PI-3-Kinase signaling, receptor-tyrosine kinase (RTK)/RAS/MAP-Kinase signaling, TGFb signaling, p53, and b-catenin/Wnt signaling)16, revealed that it is positively correlated with 3 of these cancer pathways (cell-cycle, p53, and RTK/RAS). Here, TP53 is linked to cancer.