Furthermore, although similar baseline SOFA scores, presence of sepsis, C-reactive protein levels indicate similar severity of acute illness, we did not have data on education status, insurance/socioeconomic status, PaO2:FiO2 ratio, vasopressor utilization, diagnosis of acute renal failure, or any other non-Sars-CoV-2 etiologies of sepsis—future prospective or propensity-matched design studies are indicated to evaluate any contributions of these various factors to delirium or coma and confirm our findings. This evidence concerns the gene CRP and Sepsis.