Notably, the in vitro anti-tumor results indicated that the α-IL-33 and α-ST2L did not directly inhibit cell growth or induce cell death in LLC (Fig. 3E-H) presumably due to low basal level of IL-33 secretion in lung cancer cell lines without cisplatin treatment (Fig. 4B and Fig. 4A). The gene discussed is IL33; the disease is neoplasm.