FURIN and schizophrenia: This analysis replicated schizophrenia expression signatures identified previously in a TWAS that considered cis-heritable expression in a subset of the CMC cohort2 (e.g., NAGA, Z = 7.74, P = 9.58 x 10−15; SNAP91, Z = 4.80, P = 1.61 x 10−6; TAOK2, Z = −7.44, P = 1.04 x 10−13) and in the developing brain22 (e.g., SF3B1, Z = 6.99, P = 2.78 x 10−12; MAPK3, Z = 5.68, P = 1.39 x 10−8; FURIN, Z = −8.44, P = 3.11 x 10−17).