A common genetic etiology was proposed between hypothyroidism and OLP81 and our study supports this, indicating variation at nine loci (IFIH1, LPP, CEP43, TNRC18, C12orf42, TNFSF11, ST3GAL6, IL2RA, and IKZF3) that are strongly associated with both LP and autoimmune hypothyroidism. This evidence concerns the gene LPP and hypothyroidism.