In tissue, MPs were the most active populations in all three conditions, promoting immune response, intracellular and second messenger signaling, and cellular stress and injury in stable CAD and cardiovascular signaling and disease-specific pathways in acute MI, leading to glucocorticoid-mediated CCL2 and CCL3 production in both (Figures S7C and S7D). The gene discussed is CCL2; the disease is myocardial infarction.