FYB1 and infection: Further, plaque assays were performed with the supernatants from the PR8 infected iBMMs to evaluate the kinetics of PR8 replication in WT and Adap-/- iBMMs, showing that ADAP deficiency led to a significant increase in the viral replication at 18, 24 and 48 hrs post infection relative to that in WT cells (left panel of Fig 6E).